Dr. Hilary Baldwin from the State University of New York, Brooklyn presented a paper at a seminar in San Francisco on Women’s dermatology that showed an increasing incidence in resistant acne in adult women. Topical treatments do not work very well in adults, and oral antibiotics are notorious for causing vaginal yeast infections. Spironolactone is an off-label treatment that is pretty effective but carries a black box warning because of developing tumors in mice. I find that the Smoothbeam laser is very effective for this problem, and also can reduce previous acne scarring as well as unsightly wrinkles in the face. Pantothenic acid at 500 mg twice a day can be very helpful.
See Family Practice News (click here), November 15, 2010, p. 52-3.